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PC Antikörper (Internal Region)

PC Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Hund WB, IHC (p), EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN372799
  • Target Alle PC Antikörper anzeigen
    PC (Pyruvate Carboxylase (PC))
    Bindungsspezifität
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 16
    • 15
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Schwein, Rind (Kuh), Hund
    Wirt
    • 23
    • 1
    • 1
    Ziege
    Klonalität
    • 24
    • 1
    Polyklonal
    Konjugat
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser PC Antikörper ist unkonjugiert
    Applikation
    • 24
    • 17
    • 14
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    Recognizes Pyruvate Carboxylase (PC).
    Kreuzreaktivität (Details)
    Species reactivity (expected):Bovine, Canine (Dog), Mouse, Porcine and Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Immunoaffinity Chromatography.
    Immunogen
    Synthetic peptide (C-KFKEVKKAYVEANQ) from an Internal region of Human PC.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA: 1/16000. Western blot: 0.03-0.1 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PC (Pyruvate Carboxylase (PC))
    Andere Bezeichnung
    Pyruvic Carboxylase (PC) (PC Produkte)
    Synonyme
    BcDNA antikoerper, BcDNA:GH06348 antikoerper, Dmel\\CG1516 antikoerper, PC antikoerper, pyc antikoerper, wu:fb82g08 antikoerper, wu:fj85g01 antikoerper, PCX antikoerper, BA4157 antikoerper, Pc antikoerper, Pcb antikoerper, PCB antikoerper, Pcx antikoerper, Pyruvate carboxylase antikoerper, pyruvate carboxylase b antikoerper, PYruvate Carboxylase antikoerper, pyruvate carboxylase antikoerper, pyruvate carboxylase Pyr1 antikoerper, PCB antikoerper, pcxb antikoerper, pyc-1 antikoerper, PC antikoerper, pyc antikoerper, pyr1 antikoerper, CNF00650 antikoerper, PYC1 antikoerper, Ndas_1152 antikoerper, Ilyop_2503 antikoerper, Calni_0495 antikoerper, Ftrac_1004 antikoerper, Plabr_3574 antikoerper, Sgly_2936 antikoerper, Celly_0558 antikoerper, Hipma_0131 antikoerper, Halhy_1567 antikoerper, Mesop_1269 antikoerper, Pcx antikoerper, Pc antikoerper
    Hintergrund
    Pyruvate Carboxylase (PC, PCB) requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. PCB is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.Synonyms: PCB, Pyruvate carboxylase mitochondrial
    Gen-ID
    5091
    NCBI Accession
    NP_000911
    UniProt
    P11498
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