CES1 Antikörper (Internal Region)

Produktnummer ABIN372769

Dieser Ziege Polyklonal Antikörper detektiert spezifisch CES1 in WB, IHC (p) und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CES1 Antikörper (Internal Region) (ABIN372769)

Target: CES1 (Carboxylesterase 1 (CES1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CES1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CES1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: Recognizes Carboxylesterase 1 (CES1).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide (C-NTQAAQKLKDKE) from an internal region of Human CES1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/8000. Western Blot: 0.03-0.1 μg/mL. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Andere Bezeichnung: CES1 / ACAT

Hintergrund: The enzymes of the carboxylesterase family are widely distributed and can be found in the tissues of all animals. They differ in biochemical, immunological and genetic properties and play different roles depending on which part of the organism they are expressed in. In general, these carboxylesterases are responsible for detoxification, since they are able to degrade a number of exogenous compounds such as esters, amides and thioesters. Esterases cause esters to split into an acid and an alcohol within the human body, especially the ones found in nucleic acids (phosphodiester bonds) and lipids. Some types of esterase are found in lysozomes and are called acid hydrolase. Other types of esterase include: - Cholesterol esterase - Also referred to as cholesterol ester hydrolase and sterol esterase, cholesterol esterase is a form of esterase that occurs in the pancreas, the intestinal mucosa, the liver, and the kidney. It even occurs in the muscle. - Leukocyte esterase - Leukocyte esterase is used to determine whether or not white blood cells and irregularities that could cause infections are in the body. - Cholinesterase - Cholinesterase consists of acetylcholinesterase, which is found in the blood, and pseudocholinesterase, which is found in the blood plasma of the liver.Synonyms: Acyl coenzyme A:cholesterol acyltransferase, Brain carboxylesterase hBr1, CES2, Egasyn, HMSE, Liver carboxylesterase 1, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, SES1, Serine esterase 1, Triacylglycerol hydrolase, hBr1

Gen-ID: 1066

NCBI Accession: NP_001020365

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process