SYT1 Antikörper (pThr202)
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- Target Alle SYT1 Antikörper anzeigen
- SYT1 (Synaptotagmin I (SYT1))
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Bindungsspezifität
- pThr202
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Reaktivität
- Human, Ratte, Maus, Rind (Kuh), Huhn, Hund, Zebrafisch (Danio rerio), Non-Human Primate
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SYT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)
- Spezifität
- This antibody recognizes the ~60k-62k synaptotagmin protein phosphorylated at Thr202 in Western Blots of Rat brain lysate. The immunolabeling is completely eliminated by lambda-phosphatase treatment.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Human, Bovine, Canine, Chicken, Mouse, non-Human Primate and Zebrafish.
Species reactivity (tested):Rat. - Aufreinigung
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
- Immunogen
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr202 of Synaptotagmin.
- Isotyp
- IgG
- Top Product
- Discover our top product SYT1 Primärantikörper
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- Applikationshinweise
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Dot blot: 1/1,000. Western blot: 1/1,000. Immunohistochemistry: 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Target
- SYT1 (Synaptotagmin I (SYT1))
- Andere Bezeichnung
- Synaptotagmin-1 (SYT1 Produkte)
- Synonyme
- P65 antikoerper, SVP65 antikoerper, SYT antikoerper, CG3139 antikoerper, D. Syt I antikoerper, DSYT antikoerper, DSYT2 antikoerper, DSypt antikoerper, DSyt antikoerper, Dmel\\CG3139 antikoerper, Droso1 antikoerper, Dsyt2 antikoerper, SYT I antikoerper, SYT1 antikoerper, Syt antikoerper, Syt 1 antikoerper, Syt I antikoerper, Syt-1 antikoerper, SytI antikoerper, dSYT antikoerper, dsyt1 antikoerper, dsytI antikoerper, l(2)23AB1 antikoerper, l(2)23Ba antikoerper, l(2)k05909 antikoerper, syt antikoerper, syt 1 antikoerper, syt I antikoerper, syt-1 antikoerper, syt1 antikoerper, sytI antikoerper, AW124717 antikoerper, G630098F17Rik antikoerper, Syti antikoerper, GB20036 antikoerper, DKFZP459P193 antikoerper, svp65 antikoerper, p65 antikoerper, wu:fj41c01 antikoerper, wu:fk56d05 antikoerper, zgc:92899 antikoerper, synaptotagmin 1 antikoerper, Synaptotagmin 1 antikoerper, synaptotagmin I antikoerper, synaptotagmin-1 antikoerper, synaptotagmin, p65 antikoerper, synaptotagmin Ia antikoerper, synaptotagmin 1 L homeolog antikoerper, SYT1 antikoerper, Syt1 antikoerper, Tsp_06980 antikoerper, Tsp_08220 antikoerper, syt1 antikoerper, LOC100533340 antikoerper, syt1a antikoerper, syt1.L antikoerper
- Hintergrund
- Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001, Wang et al., 2003). Moreover, recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin's ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999, Lee et al., 2004).Synonyms: SYT1, SYT2, SYT3, SYT4, SYT5
- Gen-ID
- 6857
- NCBI Accession
- NP_001129277
- UniProt
- P21579
- Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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