SYT1 Antikörper

Produktnummer ABIN372723

Der Kaninchen Polyklonal anti-SYT1 Antikörper (ABIN372723) detektiert spezifisch SYT1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Huhn und Non-Human Primate.

Kurzübersicht für SYT1 Antikörper (ABIN372723)

Target: SYT1 (Synaptotagmin I (SYT1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Huhn, Non-Human Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SYT1 Antikörper

Spezifität: This antibody recognizes the ~65k Synaptotagmin I protein.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Mouse, Bovine, Chicken and non-Human Primates.
Species reactivity (tested):Rat.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide corresponding to amino acid residues within the Synaptotagmin-1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu SYT1

Target: SYT1 (Synaptotagmin I (SYT1))

Andere Bezeichnung: Synaptotagmin-1

Hintergrund: Synaptotagmin-1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release (Littleton and Bellen 1995). Recent studies indicate that Synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion (Zhang et al., 2002). It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size (Poskanzer et al., 2006).Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65

Gen-ID: 6857

NCBI Accession: NP_001129277

UniProt: P21579

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport