SNAP25 Antikörper (C-Term)
Kurzübersicht für SNAP25 Antikörper (C-Term) (ABIN372714)
Target
Alle SNAP25 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody recognizes the ~25k SNAP25 protein.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Human, Bovine, Canine, Chicken, Mouse, Guinea Pig, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat. -
Aufreinigung
- Affinity Chromatography.
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Immunogen
- Peptide corresponding to amino acid residues from the C-terminal region of rat SNAP25 conjugated to keyhole limpet hemocyanin (KLH).
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Isotyp
- IgG
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Applikationshinweise
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at-20 °C.
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- SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
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Andere Bezeichnung
- SNAP25
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Hintergrund
- SNAP25 (Synaptosomal associated protein of 25 kDa) is a presynaptic plasma membrane protein that is widely distributed throughout the brain and involved in the regulation of neurotransmitter release. Decreased levels of SNAP25 have been found in the brains of patients with Down Syndrome and Alzheimer's Disease (Greber et al.,1999). In addition, a significant reduction in the hippocampal expression of SNAP25 has also been found in patients with Schizophrenia (Fatemi et al., 2001).Synonyms: RIC4, SNAP, SNAP-25, SUP, Super Protein, Synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, ric-4
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Gen-ID
- 25012
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NCBI Accession
- NP_112253
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UniProt
- P60881
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Target
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