RPH3A Antikörper (C-Term)
Kurzübersicht für RPH3A Antikörper (C-Term) (ABIN372709)
Target
Alle RPH3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody recognizes the ~82k Rabphilin-3A protein.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Human, Bovine, Canine and non-Human Primates.
Species reactivity (tested):Rat. -
Aufreinigung
- Affinity Chromatography.
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Immunogen
- Synthetic peptide corresponding to amino acid residues from the C-terminal region of Rabphilin-3A.
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Isotyp
- IgG
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Applikationshinweise
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at-20 °C.
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- RPH3A (Rabphilin 3A (RPH3A))
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Andere Bezeichnung
- Rabphilin-3A / RPH3A
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Hintergrund
- Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001).Synonyms: Exophilin 1, Exophilin-1, KIAA0985, Rabphilin 3A
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Gen-ID
- 171039
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NCBI Accession
- NP_598202
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UniProt
- P47709
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Pathways
- Synaptic Vesicle Exocytosis
Target
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