STK10-A Antikörper (pSer482, pSer486, pSer490)

Produktnummer ABIN372704

Der Kaninchen Polyklonal Anti-STK10-A-Antikörper wurde für WB validiert. Er ist geeignet, STK10-A in Proben von Human, Maus, Zebrafisch (Danio rerio), Ratte und Xenopus laevis zu detektieren.

Kurzübersicht für STK10-A Antikörper (pSer482, pSer486, pSer490) (ABIN372704)

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Reaktivität: Human, Maus, Zebrafisch (Danio rerio), Ratte, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK10-A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STK10-A Antikörper

Bindungsspezifität: pSer482, pSer486, pSer490

Spezifität: This antibody recognizes the ~120k PLKK protein phosphorylated at Ser482,486,490.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Mouse, Rat and Zebrafish.
Species reactivity (tested):Xenopus.

Aufreinigung: Sequential Chromatography on phospho- and dephosphopeptide affinity columns.

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho- Ser482,486,490 of Xenopus polo-like kinase kinase (PLKK).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu STK10-A

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Andere Bezeichnung: PLKK1

Hintergrund: Considerable evidence indicates that a polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.Synonyms: Polo-like kinase kinase 1, stk10, xPlkk1

Gen-ID: 373731

NCBI Accession: NP_001079164

UniProt: Q9YHC9