Periostin Antikörper

Produktnummer ABIN372701

Der Kaninchen Polyklonal Anti-Periostin-Antikörper wurde für WB, IHC (p) und IHC (fro) validiert. Er ist geeignet, Periostin in Proben von Human, Maus, Ratte, Huhn, Säugetier, Amphibien und Fisch zu detektieren.

Kurzübersicht für Periostin Antikörper (ABIN372701)

Target: Periostin (POSTN)

Reaktivität: Human, Maus, Ratte, Huhn, Säugetier, Amphibien, Fisch

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Periostin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Periostin Antikörper

Spezifität: This antibody recognizes the three Periostin bands around ~93 kDa in Mouse lung extract. The immunogenic peptide is present in all known splice variants of Periostin and therefore this antibody recognizes all known molecular forms of Periostin.

Kreuzreaktivität (Details): Species reactivity (expected):Mammalia, Birds, Amphibians and Fishes.
Species reactivity (tested):Human, Chicken, Mouse and Rat.

Aufreinigung: Affinity Chromatography.

Immunogen: Peptide from fasciclin domain 1 of Mouse Periostin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1000. Immunohistochemistry: 1/100. Immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrievalprotocol (incubate slides for 20 minutes at 90 °C in 10 mM sodium citrate ( pH 6.0)/ 0.1 % Tween-20).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C. For long term store the antibody (in aliquots) at -80 °C.

Details zu Periostin

Target: Periostin (POSTN)

Andere Bezeichnung: Periostin

Hintergrund: Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 2004). Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 2008)Synonyms: OSF-2, OSF2, Osteoblast-specific factor 2, PN, POSTN

Gen-ID: 10631

NCBI Accession: NP_001129406

UniProt: Q15063