NEFM Antikörper (C-Term)

Produktnummer ABIN372674

Der Huhn Polyklonal anti-NEFM Antikörper wird verwendet zum Nachweis von NEFM in Proben von Human, Ratte, Maus und Huhn. Er wurde validiert für WB, IF und IHC (fro).

Kurzübersicht für NEFM Antikörper (C-Term) (ABIN372674)

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Reaktivität: Human, Ratte, Maus, Huhn

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser NEFM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NEFM Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody recognizes the ~145k Neurofilament M protein.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Chicken, Mouse and Rat.

Aufreinigung: Ig Fraction

Immunogen: Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1000. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu NEFM

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Andere Bezeichnung: Neurofilament M (160 kD)

Hintergrund: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (Ref.1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (Ref.2).Synonyms: (Neuronal Marker), NEF3, NEFM, NF-M, Neurofilament 3, Neurofilament medium polypeptide

Gen-ID: 24588

NCBI Accession: NP_058725

UniProt: P12839

Pathways: Brown Fat Cell Differentiation