MARCKS Antikörper (pSer152, pSer156)

Produktnummer ABIN372663

Dieses Anti-MARCKS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MARCKS in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Huhn und Xenopus laevis.

Kurzübersicht für MARCKS Antikörper (pSer152, pSer156) (ABIN372663)

Target: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCKS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MARCKS Antikörper

Bindungsspezifität: pSer152, pSer156

Kreuzreaktivität (Details): Species reactivity (expected):Bovine, Chicken, Human, Mouse, Xenopus and Zebrafish.
Species reactivity (tested):Rat.

Aufreinigung: Sequential Chromatography on phospho- and dephosphopeptide affinity columns.

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho- Ser152,156 of MARCKS.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu MARCKS

Target: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Andere Bezeichnung: MARCKS

Hintergrund: Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) is a major substrate for phosphorylation by protein kinase C (PKC) (Ouimet et al., 1990). The phosphorylation of Ser152/156 can be used as a measure of PKC activation although these sites are also phosphorylated by PRK1 (Palmer et al., 1996) MARCKS is a member of a family of calmodulin binding proteins and phosphorylation of Ser152/156 modulates the binding of MARCKS to calmodulin (Verghese et al., 1994).Synonyms: MACS, Myristoylated alanine-rich C-kinase substrate, PRKCSL

Gen-ID: 10116

UniProt: P30009