DBH Antikörper (N-Term)

Produktnummer ABIN372612

Dieses Anti-DBH-Antikörper ist ein Schaf Polyklonal-Antikörper zur Detektion von DBH in WB und IHC (p). Geeignet für Human und Non-Human Primate.

Kurzübersicht für DBH Antikörper (N-Term) (ABIN372612)

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Reaktivität: Human, Non-Human Primate

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser DBH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DBH Antikörper

Bindungsspezifität: N-Term

Spezifität: Specific for the ~75k DBH protein in Western blots.

Kreuzreaktivität (Details): Species reactivity (tested):Human and non-Human Primates.

Aufreinigung: Affinity Chromatography using a Sulfo-Link® column matrix to which the peptide immunogen was coupled.

Immunogen: Peptide from the N-terminal region of human dopamine Beta-hydroxylase (DBH), conjugated to keyhole limpet hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu DBH

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Andere Bezeichnung: Dopamine beta-Hydroxylase

Hintergrund: DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001).Synonyms: DBH, DBM, DOPO, Dopamine beta-monooxygenase

Gen-ID: 1621

NCBI Accession: NP_000778

UniProt: P09172

Pathways: Carbohydrate Homeostasis