Claudin 3 Antikörper (C-Term)

Produktnummer ABIN372578

Der Kaninchen Polyklonal anti-Claudin 3 Antikörper wird verwendet zum Nachweis von Claudin 3 in Proben von Human, Maus und Ratte. Er wurde validiert für IHC (p).

Kurzübersicht für Claudin 3 Antikörper (C-Term) (ABIN372578)

Target: Claudin 3 (CLDN3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Claudin 3 Antikörper

Bindungsspezifität: C-Term

Spezifität: Specific to Claudin 3 (CLDN3).
Cellular Localization: Cell membrane and cytoplasmic.

Kreuzreaktivität (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: A synthetic peptide derived from the C-terminus of Mouse Claudin-3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM PBS, pH 7.6 containing 15 mM Sodium Azide as preservative and 0.2 % BSA,40 % Glycerol as stabilizers.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Claudin 3

Target: Claudin 3 (CLDN3)

Andere Bezeichnung: Claudin-3 / CLDN3

Hintergrund: Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact, made up of network of strands to act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition. The protein encoded by this intronless Claudin 3 gene is also a low affinity receptor for Clostridium perfringens enterotoxin, and shares amino acid sequence similarity with a putative apoptosis related protein found in rat.Synonyms: C7orf1, CPE-R2, CPE-Receptor 2, CPETR2, Clostridium perfringens enterotoxin receptor 2, RVP1

Gen-ID: 1365

NCBI Accession: NP_001297

UniProt: O15551

Pathways: Hepatitis C