Apolipoprotein D Antikörper (N-Term)

Produktnummer ABIN372486

Dieses Anti-Apolipoprotein D-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Apolipoprotein D in WB und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für Apolipoprotein D Antikörper (N-Term) (ABIN372486)

Target: Apolipoprotein D (APOD)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Apolipoprotein D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Apolipoprotein D Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody recognizes Apolipoprotein D (APOD).

Kreuzreaktivität (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to N-terminal residues of mouse APOD.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 μg/mLImmunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Apolipoprotein D

Target: Apolipoprotein D (APOD)

Andere Bezeichnung: Apolipoprotein D (Apo D)

Hintergrund: Apolipoprotein D (APO D), a glycoprotein involved in the human plasma lipid transport system. It is a progesterone binding glycoprotein of 24,000 dalton monomer molecular size, is a constituent of high density lipoprotein in plasma. The function of apolipoprotein D in the metabolism of plasma lipoproteins is unclear but the observation that this protein forms complexes with lecithin: cholesterol acyltransferase has led to the suggestion that apolipoprotein D may be involved in cholesterol esterification and transport of substrates and products of the reaction. Apolipoprotein D is expressed in a range of normal tissues including axillary apocrine glands, adrenal cortex and corpus luteum. Peripheral nerves, pituitary, testis, cerebellum and renal tubes are also positive. APO D was first isolated in large quantity as GCDFP 24, the major protein component of most human breast cyst fluids. In recent studies, Apo D immunoreactivity has been shown to be an early indicator of prostate cancer and advanced primary prostate tumors.Synonyms: APOD, Apo-D

Molekulargewicht: 21 kDa.

Gen-ID: 347

NCBI Accession: NP_001638

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling