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Retinoid X Receptor gamma Antikörper (Hinge Region)

RXRG Reaktivität: Human, Maus, Ratte, Rind (Kuh), Non-Human Primate WB Wirt: Maus Monoclonal 1373 unconjugated
Produktnummer ABIN371840
  • Target Alle Retinoid X Receptor gamma (RXRG) Antikörper anzeigen
    Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
    Bindungsspezifität
    • 15
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Hinge Region
    Reaktivität
    • 59
    • 21
    • 18
    • 10
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Non-Human Primate
    Wirt
    • 48
    • 10
    • 1
    Maus
    Klonalität
    • 50
    • 9
    Monoklonal
    Konjugat
    • 34
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Retinoid X Receptor gamma Antikörper ist unkonjugiert
    Applikation
    • 29
    • 22
    • 13
    • 13
    • 9
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody is specific for the ~48k RAR-gamma isotype.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Bovine, Rat, Mouse and non-Human Primates.
    Species reactivity (tested):Human.
    Produktmerkmale
    Synonyms: NR2B3, Retinoic acid receptor RXR-gamma, Retinoid X receptor gamma, Nuclear receptorsubfamily 2 group B member 3
    Aufreinigung
    Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.
    Immunogen
    Hinge peptide from Human retinoid X receptor, gamma-isotype.
    Klon
    1373
    Isotyp
    IgG1
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  • Applikationshinweise
    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
    Andere Bezeichnung
    RXR-gamma / RXRG (RXRG Produkte)
    Synonyme
    NR2B3 antikoerper, RXRC antikoerper, zgc:92183 antikoerper, RXRgamma antikoerper, RXRG antikoerper, RXR-gamma antikoerper, nr2b3 antikoerper, xrxrg antikoerper, rxrc antikoerper, Nr2b3 antikoerper, NR2B1 antikoerper, RXR antikoerper, rxra antikoerper, rxrg antikoerper, retinoid X receptor gamma antikoerper, retinoid X receptor, gamma b antikoerper, retinoid X receptor gamma L homeolog antikoerper, retinoid x receptor, gamma a antikoerper, RXRG antikoerper, rxrgb antikoerper, rxrg.L antikoerper, rxrg antikoerper, Rxrg antikoerper, RXRGAMMA antikoerper, rxrga antikoerper
    Hintergrund
    Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: NR2B3, Nuclear receptor subfamily 2 group B member 3, Retinoic acid receptor RXR-gamma, Retinoid X receptor gamma
    Gen-ID
    6258
    UniProt
    P48443
    Pathways
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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