Retinoid X Receptor beta Antikörper

Produktnummer ABIN371839

Produktdetails anti-Retinoid X Receptor beta Antikörper

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoid X Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody is specific for the ~48k RAR-beta isotype.

Kreuzreaktivität (Details): Species reactivity (expected):Human.
Species reactivity (tested):Mouse and Rat

Produktmerkmale: Synonyms: NR2B2, H-2RIIBP, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta, Nuclearreceptor subfamily 2 group B member 2, Nuclear Receptor Coregulator 1

Aufreinigung: Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

Immunogen: Hinge peptide corresponding to amino acids from Human, Mouse and Rat retinoid Xreceptor, beta-isotype.

Klon: 147

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Andere Bezeichnung: RXR-beta / RXRB (RXRB Produkte)

Synonyme: DAUDI6 antikoerper, H-2RIIBP antikoerper, NR2B2 antikoerper, RCoR-1 antikoerper, RXR-beta antikoerper, RXRbeta antikoerper, rxrb antikoerper, RXRB antikoerper, nr2b2 antikoerper, daudi6 antikoerper, rcor-1 antikoerper, h-2riibp antikoerper, NR2B2-A antikoerper, RXR antikoerper, RXRA antikoerper, etID309733.19 antikoerper, rxre antikoerper, wu:fb93c09 antikoerper, AL023085 antikoerper, Nr2b2 antikoerper, Rub antikoerper, rxrd antikoerper, unp286 antikoerper, retinoid X receptor beta antikoerper, retinoid X receptor beta S homeolog antikoerper, retinoid x receptor, beta a antikoerper, retinoid x receptor, beta b antikoerper, RXRB antikoerper, Rxrb antikoerper, rxrb.S antikoerper, rxrb antikoerper, rxrba antikoerper, rxrbb antikoerper

Hintergrund: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: H-2RIIBP, NR2B2, Nuclear Receptor Coregulator 1, Nuclear receptor subfamily 2 group B member 2, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta

Gen-ID: 6257

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway