Retinoid X Receptor beta Antikörper

Produktnummer ABIN371839

Dieser Maus Monoklonal Antikörper detektiert spezifisch Retinoid X Receptor beta in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Retinoid X Receptor beta Antikörper (ABIN371839)

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoid X Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 147

Produktdetails anti-Retinoid X Receptor beta Antikörper

Spezifität: This antibody is specific for the ~48k RAR-beta isotype.

Kreuzreaktivität (Details): Species reactivity (expected):Human.
Species reactivity (tested):Mouse and Rat

Produktmerkmale: Synonyms: NR2B2, H-2RIIBP, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta, Nuclearreceptor subfamily 2 group B member 2, Nuclear Receptor Coregulator 1

Aufreinigung: Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

Immunogen: Hinge peptide corresponding to amino acids from Human, Mouse and Rat retinoid Xreceptor, beta-isotype.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Andere Bezeichnung: RXR-beta / RXRB

Hintergrund: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: H-2RIIBP, NR2B2, Nuclear Receptor Coregulator 1, Nuclear receptor subfamily 2 group B member 2, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta

Gen-ID: 6257

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway