Retinoic Acid Receptor beta Antikörper (N-Term)

Produktnummer ABIN371838

Produktdetails anti-Retinoic Acid Receptor beta Antikörper

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoic Acid Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody is specific for the ~48k RAR-beta isotype.

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog), Guinea Pig, Mouse and Rat.
Species reactivity (tested):Human.

Produktmerkmale: Synonyms: RAR-epsilon, HAP, NR1B2, Retinoic acid receptor beta, HBV-activated protein, Nuclearreceptor subfamily 1 group B member 2

Aufreinigung: Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

Immunogen: Peptide corresponding to amino acids from N-terminal region of human retinoic acidreceptor, beta-isotype. Remarks: The antigen is identical in both beta-1 and beta-2 isoforms.

Klon: 336

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Retinoic Acid Receptor beta

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Andere Bezeichnung: RAR-beta / RARB (RARB Produkte)

Synonyme: RARB antikoerper, nRARs antikoerper, HAP antikoerper, NR1B2 antikoerper, RRB2 antikoerper, A830025K23 antikoerper, Hap antikoerper, Nr1b2 antikoerper, RARbeta2 antikoerper, RARBETA antikoerper, retinoic acid receptor beta antikoerper, retinoic acid receptor, beta antikoerper, RARB antikoerper, Rarb antikoerper

Hintergrund: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: HAP, HBV-activated protein, NR1B2, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon, Retinoic acid receptor beta

Gen-ID: 5915

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway