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Retinoic Acid Receptor beta Antikörper (N-Term)

Dieses Anti-Retinoic Acid Receptor beta-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Retinoic Acid Receptor beta in WB. Geeignet für Human, Maus, Ratte, Hund und Meerschweinchen.
Produktnummer ABIN371838

Kurzübersicht für Retinoic Acid Receptor beta Antikörper (N-Term) (ABIN371838)

Target

Alle Retinoic Acid Receptor beta (RARB) Antikörper anzeigen
Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Reaktivität

  • 75
  • 39
  • 6
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 1
Human, Maus, Ratte, Hund, Meerschweinchen

Wirt

  • 65
  • 10
Maus

Klonalität

  • 65
  • 10
Monoklonal

Konjugat

  • 41
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Retinoic Acid Receptor beta Antikörper ist unkonjugiert

Applikation

  • 62
  • 30
  • 18
  • 13
  • 13
  • 12
  • 8
  • 8
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

336
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Spezifität

    This antibody is specific for the ~48k RAR-beta isotype.

    Kreuzreaktivität (Details)

    Species reactivity (expected):Canine (Dog), Guinea Pig, Mouse and Rat.
    Species reactivity (tested):Human.

    Produktmerkmale

    Synonyms: RAR-epsilon, HAP, NR1B2, Retinoic acid receptor beta, HBV-activated protein, Nuclearreceptor subfamily 1 group B member 2

    Aufreinigung

    Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

    Immunogen

    Peptide corresponding to amino acids from N-terminal region of human retinoic acidreceptor, beta-isotype. Remarks: The antigen is identical in both beta-1 and beta-2 isoforms.

    Isotyp

    IgG1
  • Applikationshinweise

    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Haltbarkeit

    12 months
  • Target

    Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

    Andere Bezeichnung

    RAR-beta / RARB

    Hintergrund

    Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: HAP, HBV-activated protein, NR1B2, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon, Retinoic acid receptor beta

    Gen-ID

    5915

    UniProt

    P10826

    Pathways

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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