KRT8 Antikörper (C-Term)
Kurzübersicht für KRT8 Antikörper (C-Term) (ABIN371614)
Target
Alle KRT8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody reacts specifically with Cytokeratin 8 and recombinant C-terminal Keratin 8.
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Produktmerkmale
- Synonyms: KRT8, CYK8, Cytokeratin-8, CK8, Keratin-8, K8, Cytokeratin endo A, Keratin, type IIcytoskeletal 8
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Aufreinigung
- Purified
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Immunogen
- Recombinant C-terminal fragment of Keratin 8.
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Isotyp
- IgG2a
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Applikationshinweise
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ELISA. Western Blot: < / = 1-2 μg/mL. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections): 10 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.1 mg/mL
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Buffer
- 100 mM Borate buffered saline, pH 8.0 without preservatives or amine-containing buffer salts.
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Konservierungsmittel
- Without preservative
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- KRT8 (Keratin 8 (KRT8))
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Andere Bezeichnung
- Cytokeratin 8
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Hintergrund
- Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30 % sequence homology. (Ref.1-5) Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 8 (55 kDa) belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. It is expressed in all simple type epithelia tissues (e.g., liver, pancreas, kidney, gut epithelial lining) but not in stratified squamous epithelia. Cytokeratin 8 is also present in the majority of adenocarcinomas and ductal carcinomas but is absent in squamous cell carcinomas.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8
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Gen-ID
- 3856
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UniProt
- P05787
Target
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