CD43 Antikörper
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- Target Alle CD43 (SPN) Antikörper anzeigen
- CD43 (SPN) (Sialophorin (SPN))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD43 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This antibody recognizes CD43.
- Produktmerkmale
- Synonyms: Leukocyte sialoglycoprotein, Sialophorin, Galactoglycoprotein, SPN
- Klon
- DF-T1
- Isotyp
- IgG1
- Top Product
- Discover our top product SPN Primärantikörper
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anti-Sialophorin (SPN) antibody
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anti-Sialophorin (SPN) antibody (FITC)SPN Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-59 FITC
anti-Sialophorin (SPN) antibody (Biotin)SPN Reaktivität: Human FACS, WB, IHC (p), IP Wirt: Maus Monoclonal MEM-59 Biotin
anti-Sialophorin (SPN) antibody (PE)SPN Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-59 PE
anti-Sialophorin (SPN) antibodySPN Reaktivität: Human, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Flow Cytometry: < / = 1 μg/10^6 cells. Immunohistochemistry on Frozen and Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- CD43 (SPN) (Sialophorin (SPN))
- Andere Bezeichnung
- CD43 / Leukosialin (SPN Produkte)
- Hintergrund
- CD43 is one of the major glycoproteins of thymocytes and T lymphocytes, it plays a role in the physicochemical properties of the T cell surface and in lectin binding. CD43 presents carbohydrate ligands to selectins. It has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. The antigen is a counter receptor for SN/Siglec1. During T cell activation CD43 is actively removed from the T cell antigen presenting cell contact site suggesting a negative regulatory role in adaptive immune response. CD43 is expressed by the majority of leucocytes, with the exception of most B cells. However CD43 expression is seen in some cases of B cell lymphocytic lymphoma and centrocytic lymphoma.Synonyms: Galactoglycoprotein, Leukocyte sialoglycoprotein, SPN, Sialophorin
- Gen-ID
- 6693
- UniProt
- P16150
- Pathways
- Regulation of Leukocyte Mediated Immunity
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