Bu-1b Antikörper

Produktnummer ABIN371415

Produktdetails anti-Bu-1b Antikörper

Target: Bu-1b (Bu-1b (B Cell Surface Alloantigens) (Bu-1b))

Reaktivität: Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Bu-1b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktmerkmale: Synonyms: B6.2, Bu1b

Aufreinigung: Purified

Immunogen: Bursal cells from 2- to 5-week-old CHA (Bu-1b) strain Chickens.

Klon: 5-11G2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: < / = 1 μg/10^6 cells. Immunoprecipitation. Immunohistochemistry on Frozen Sections. (Ref.3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Bu-1b

Target: Bu-1b (Bu-1b (B Cell Surface Alloantigens) (Bu-1b))

Andere Bezeichnung: Bu-1b (Bu-1b Produkte)

Synonyme: B6.2 antikoerper, Bu-1 antikoerper, Bu-1b antikoerper, B6.1 antikoerper, LOC396098 antikoerper

Hintergrund: Bu1b is expressed on chicken B cells throughout most of their development, as well as on some non lymphoid cells. It has no recognizable similarity to known mammalian molecules and therefore represents a unique B cell marker. Its presence in chickens may be related to differences in the properties of B cell development between chickens and mammalian species. Chicken Bu1b, a product of the Bu1b allele, is expressed on the cell surface as a disulfide linked homodimer. In 10 week old H.B15 and H.B2 chickens, Bu1 is found on 85 to 90 % of bursal cells, 2 to 8 % of thymocytes, 15 to 27 % of spleen cells, and 2 to 18 % of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes, but not on granulocytes, erythrocytes or thrombocytes. In chickens heterozygous for the Bu1 alleles (Bu1 a/b), Bu1a does not exhibit allelic exclusion.Synonyms: B6.2, chicken B-cell marker

UniProt: Q90747