T Cell Receptor (TCR) V beta 1 Antikörper

Produktnummer ABIN371346

Dieses Anti--Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von in FACS, Func, IHC (fro) und IP. Geeignet für Huhn.

Kurzübersicht für T Cell Receptor (TCR) V beta 1 Antikörper (ABIN371346)

Target: T Cell Receptor (TCR) V beta 1

Reaktivität: Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Klon: TCR2

Produktdetails

Produktmerkmale: Synonyms: TCR-Vbeta1, Vbeta-1, VB1, TCRA, TCRB, TCR-VB1, T Cell Receptor alpha/beta

Aufreinigung: Purified

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections). (Ref.7)Immunoprecipitation. In ovo suppression of the development of TCR-Vbeta 1. (Ref.5,6)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Antigendetails

Target: T Cell Receptor (TCR) V beta 1

Andere Bezeichnung: T Cell Receptor (TCR) V beta-1

Hintergrund: The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.Synonyms: T Cell Receptor alpha/beta, TCR-VB1, TCR-Vbeta1, TCRA, TCRB, VB1, Vbeta-1