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CD1a Antikörper (FITC)

Dieses Anti-CD1a-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD1a in FACS. Geeignet für Schwein. Dieses Primary Antibody wurde in 24+ Publikationen zitiert.
Produktnummer ABIN371280

Kurzübersicht für CD1a Antikörper (FITC) (ABIN371280)

Target

Alle CD1a Antikörper anzeigen
CD1a

Reaktivität

  • 173
  • 20
  • 10
  • 6
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Schwein

Wirt

  • 118
  • 58
Maus

Klonalität

  • 139
  • 36
  • 1
Monoklonal

Konjugat

  • 83
  • 12
  • 10
  • 9
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD1a Antikörper ist konjugiert mit FITC

Applikation

  • 106
  • 58
  • 48
  • 44
  • 28
  • 27
  • 12
  • 12
  • 11
  • 11
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

04-07-76
  • Spezifität

    This antibody is specific for Porcine CD1 (Mr 43-49 kDa).

    Produktmerkmale

    Synonyms: T6/Leu-6, hTa1, T-cell surface glycoprotein CD1a, T-cell surface antigen T6/Leu-6, hTa1thymocyte antigen

    Isotyp

    IgG2a
  • Applikationshinweise

    Flow Cytometry: < / = 1 μg/10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.5 mg/mL

    Buffer

    PBS containing 0.09 % Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Haltbarkeit

    12 months
  • Lourido, Calamia, Fernández-Puente, Mateos, Oreiro, Blanco, Ruiz-Romero: "Secretome analysis of human articular chondrocytes unravels catabolic effects of nicotine on the joint." in: Proteomics. Clinical applications, Vol. 10, Issue 6, pp. 671-80, (2017) (PubMed).

    Seifert, Werba, Tiwari, Giao Ly, Alothman, Alqunaibit, Avanzi, Barilla, Daley, Greco, Torres-Hernandez, Pergamo, Ochi, Zambirinis, Pansari, Rendon, Tippens, Hundeyin, Mani, Hajdu, Engle, Miller: "The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression." in: Nature, Vol. 532, Issue 7598, pp. 245-9, (2016) (PubMed).

    Polioudaki, Agelaki, Chiotaki, Politaki, Mavroudis, Matikas, Georgoulias, Theodoropoulos et al.: "Variable expression levels of keratin and vimentin reveal differential EMT status of circulating tumor cells and correlation with clinical characteristics and outcome of patients with metastatic ..." in: BMC cancer, Vol. 15, pp. 399, (2016) (PubMed).

    Kim, Son, Bae, Lee, Lee, Jo, Kim, Yang: "Administration of granulocyte colony-stimulating factor with radiotherapy promotes tumor growth by stimulating vascularization in tumor-bearing mice." in: Oncology reports, Vol. 34, Issue 1, pp. 147-54, (2016) (PubMed).

    Ohkubo, Kodama, Muraoka, Hitotsumachi, Yoshimura, Kitade, Hashimoto, Ito, Gomori, Takahashi, Shibata, Kanoh, Yonekura: "TAS-116, a highly selective inhibitor of heat shock protein 90α and β, demonstrates potent antitumor activity and minimal ocular toxicity in preclinical models." in: Molecular cancer therapeutics, Vol. 14, Issue 1, pp. 14-22, (2015) (PubMed).

    Ott, Litzenburger, Rauschenbach, Bunse, Ochs, Sahm, Pusch, Opitz, Blaes, von Deimling, Wick, Platten: "Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway." in: Glia, Vol. 63, Issue 1, pp. 78-90, (2015) (PubMed).

    Todorovic, Koetsier, Godsel, Green: "Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation." in: Molecular biology of the cell, Vol. 25, Issue 23, pp. 3749-64, (2015) (PubMed).

    Leclercq, Prunier, Thomas, Merlot: "Neonatal surgical castration of male pigs reduces thymic growth but has moderate consequences on thymocytes." in: Journal of animal science, Vol. 92, Issue 6, pp. 2415-21, (2014) (PubMed).

    Grün, Schmucker, Schalk, Flauger, Stefanski: "Characterization of the adaptive immune response following immunization in pregnant sows (Sus scrofa) kept in two different housing systems." in: Journal of animal science, Vol. 92, Issue 8, pp. 3388-97, (2014) (PubMed).

    Dutheil, Smith, Agúndez, Vincent-Mistiaen, Escalante, Linden, Henckaerts: "Adeno-associated virus Rep represses the human integration site promoter by two pathways that are similar to those required for the regulation of the viral p5 promoter." in: Journal of virology, Vol. 88, Issue 15, pp. 8227-41, (2014) (PubMed).

    Brodehl, Dieding, Klauke, Dec, Madaan, Huang, Gargus, Fatima, Saric, Cakar, Walhorn, Tönsing, Skrzipczyk, Cebulla, Gerdes, Schulz, Gummert, Svendsen, Olesen, Anselmetti, Christensen, Kimonis, Milting: "The novel desmin mutant p.A120D impairs filament formation, prevents intercalated disk localization, and causes sudden cardiac death." in: Circulation. Cardiovascular genetics, Vol. 6, Issue 6, pp. 615-23, (2014) (PubMed).

    Debeer, Le Luduec, Kaiserlian, Laurent, Nicolas, Dubois, Kanitakis: "Comparative histology and immunohistochemistry of porcine versus human skin." in: European journal of dermatology : EJD, Vol. 23, Issue 4, pp. 456-66, (2013) (PubMed).

    Chen, Dong, Shen, Zhao, Ju, Yi, Zhang, Kang, Chen: "Classical swine fever virus suppresses maturation and modulates functions of monocyte-derived dendritic cells without activating nuclear factor kappa B." in: Research in veterinary science, Vol. 93, Issue 1, pp. 529-37, (2012) (PubMed).

    Cartault, Munier, Benko, Desguerre, Hanein, Boddaert, Bandiera, Vellayoudom, Krejbich-Trotot, Bintner, Hoarau, Girard, Génin, de Lonlay, Fourmaintraux, Naville, Rodriguez, Feingold, Renouil, Munnich et al.: "Mutation in a primate-conserved retrotransposon reveals a noncoding RNA as a mediator of infantile encephalopathy. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 13, pp. 4980-5, (2012) (PubMed).

    Margarit, Taylor, Roberts, Hopkins, Davies, Brenton, Conlan, Bunkheila, Joels, White, Gonzalez: "MUC1 as a discriminator between endometrium from fertile and infertile patients with PCOS and endometriosis." in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 12, pp. 5320-9, (2011) (PubMed).

    Facci, Auray, Buchanan, van Kessel, Thompson, Mackenzie-Dyck, Babiuk, Gerdts: "A comparison between isolated blood dendritic cells and monocyte-derived dendritic cells in pigs." in: Immunology, Vol. 129, Issue 3, pp. 396-405, (2010) (PubMed).

    Diaz-San Segundo, Moraes, de Los Santos, Dias, Grubman: "Interferon-induced protection against foot-and-mouth disease virus infection correlates with enhanced tissue-specific innate immune cell infiltration and interferon-stimulated gene expression." in: Journal of virology, Vol. 84, Issue 4, pp. 2063-77, (2010) (PubMed).

    Kapoor, Bartoszewski, Qadri, Bebok, Bubien, Fuller, Benos: "Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 24526-41, (2009) (PubMed).

    Layton, Bean, Dodge, Strom, Sandrin, Ierino: "Differential cytokine expression and regulation of human anti-pig xenogeneic responses by modified porcine dendritic cells." in: Xenotransplantation, Vol. 15, Issue 4, pp. 257-67, (2008) (PubMed).

    Nfon, Dawson, Toka, Golde: "Langerhans cells in porcine skin." in: Veterinary immunology and immunopathology, Vol. 126, Issue 3-4, pp. 236-47, (2008) (PubMed).

  • Target

    CD1a

    Andere Bezeichnung

    CD1a

    Hintergrund

    All CD1 Molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 Molecules are involved in T cell activation. In contrast to MHC, however, CD1 Molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.Synonyms: T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6/Leu-6, hTa1, hTa1 thymocyte antigen

    Gen-ID

    396785

    UniProt

    Q9XS72

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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