Integrin beta 7 Antikörper

Produktnummer ABIN371134

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch Integrin beta 7 in FACS, IHC (fro) und Func. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Integrin beta 7 Antikörper (ABIN371134)

Target: Integrin beta 7 (ITGB7)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 7 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon: DATK32

Produktdetails anti-Integrin beta 7 Antikörper

Spezifität: This antibody is specific to mouse LPAM1 (Integrin alpha 4 beta 7). It recognises a conformational epitope on the heterodimer.

Produktmerkmale: Synonyms: Integrin alpha-4/beta-7, Integrin alpha 4, Integrin beta 7, ITGA4, ITGB7, LPAM1, CD49d,VLA-4, Lymphocyte Peyer PatchAdhesion Molecule

Endotoxin-Niveau: Low Endotoxin

Immunogen: AKR/Cum mouse spontaneous T lymphoma cell line TK1. (Ref. 1)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. (Ref.1-4)Immunohistochemistry on Frozen Sections. (Ref.3)Induction of homotypic cellular aggregation. Blockade of binding to cell adhesion molecules.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing no preservatives.

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted in (aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Integrin beta 7

Target: Integrin beta 7 (ITGB7)

Andere Bezeichnung: Integrin beta-7

Hintergrund: The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as Integrin alpha 4 beta 7 is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (Ref.1-4)Synonyms: Adhesion Molecule, CD49d, ITGA4, ITGB7, Integrin alpha 4, Integrin alpha-4/beta-7, Integrin beta 7, LPAM1, Lymphocyte Peyer Patch, VLA-4

Gen-ID: 16421

UniProt: P26011

Pathways: Integrin Complex