ENPEP
Reaktivität: Human
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Flow Cytometry. (Ref.12)Immunoprecipitation. (Ref.12) Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
ENPEP
(Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP))
BP1, also known as Ly51/6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. (Ref.1,2) Originally identified on the surface of pre-B cell lymphomas (Ref.1,3) the cDNA encoding BP1 has been cloned and found to represent Aminopeptidase A. (Ref.4,5) It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of Mouse tissues known to possess aminopeptidase activity. (Ref.6-8) Subsets of normal bone marrow pre-B and B cells express low levels of BP1, which is rapidly upregulated on pre-B cells in the presence of IL-7. (Ref.9,10) The BP1 marker is commonly used to identify B cells in different stages of development. (Ref.11)Synonyms: Aminopeptidase A, Differentiation antigen gp160, EAP, ENPEP