HPV16 E7 Antikörper

Produktnummer ABIN363827

Der Maus Monoklonal Anti-HPV16 E7 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, HPV16 E7 in Proben von Human Papillomavirus (HPV) zu detektieren.

Kurzübersicht für HPV16 E7 Antikörper (ABIN363827)

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Reaktivität: Human Papillomavirus (HPV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HPV16 E7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 716-D1

Produktdetails anti-HPV16 E7 Antikörper

Spezifität: Recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. Reacts with both the monomer and dimer forms of the E7 protein of HPV-18.

Aufreinigung: Affinity purified

Immunogen: Oncoprotein E7 from human papillomavirus 16.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Human Papillomavirus

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu HPV16 E7

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Andere Bezeichnung: HPV16 E7

Substanzklasse: Viral Protein

Hintergrund: Name/Gene ID: HPV16-E7

Synonyms: HPV16-E7

Gen-ID: 1489079