PRDM1 Antikörper (AA 199-409)
Kurzübersicht für PRDM1 Antikörper (AA 199-409) (ABIN363225)
Target
Alle PRDM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 199-409
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Spezifität
- Reacts with ~98 kDa BLIMP-1 from mouse, pig and human
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Kreuzreaktivität (Details)
- May cross reacts with the beta form (~80 kDa).
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Aufreinigung
- Purified (protein G)
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Immunogen
- A fragment of the mouse Blimp-1 (residues 199-409)
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Isotyp
- IgG1
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Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ELISA: 1/100 to 1/2000 - ICC/ IF: 1/50 to 1/100 - IHC: 1/200 -FC: 8 μg/mL (for 2 x 10E6 cells/mL) - WB: 1/1000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.2 mg/mL
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Buffer
- , Sodium azide 0.1 %
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Haltbarkeit
- 6 months
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- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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Andere Bezeichnung
- B Lymphocyte-Induced Maturation Protein-1 (BLIMP-1)
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Hintergrund
- Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus.It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages.Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells.Blimp-1 has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.
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Gen-ID
- 639
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UniProt
- O75626
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Pathways
- Regulation of Muscle Cell Differentiation
Target
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