DAB1 Antikörper (AA 230-234)

Produktnummer ABIN362934

Der Kaninchen Polyklonal Anti-DAB1-Antikörper wurde für IHC validiert. Er ist geeignet, DAB1 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für DAB1 Antikörper (AA 230-234) (ABIN362934)

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAB1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-DAB1 Antikörper

Bindungsspezifität: AA 230-234

Spezifität: The antibody detects endogenous level of total Dab1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Peptide sequence around AA 230-234 (G-V-Y-D-V) derived from Human Dab1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu DAB1

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Andere Bezeichnung: Dab1

Hintergrund: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Molekulargewicht: 80 kDa

NCBI Accession: NP_066566

UniProt: O75553