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Tyrosine Hydroxylase Antikörper (pSer19)

Der Kaninchen Polyklonal anti-Tyrosine Hydroxylase Antikörper (ABIN362428) detektiert spezifisch Tyrosine Hydroxylase in IF. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.
Produktnummer ABIN362428
378,40 €
Zzgl. Versandkosten 20,00 € und MwSt
Lieferung nach: Deutschland
Lieferung in 10 bis 14 Werktagen

Kurzübersicht für Tyrosine Hydroxylase Antikörper (pSer19) (ABIN362428)

Target

Alle Tyrosine Hydroxylase (TH) Antikörper anzeigen
Tyrosine Hydroxylase (TH)

Reaktivität

  • 147
  • 140
  • 116
  • 11
  • 9
  • 9
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Ratte

Wirt

  • 143
  • 36
  • 6
  • 5
  • 2
Kaninchen

Klonalität

  • 125
  • 67
Polyklonal

Konjugat

  • 119
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Tyrosine Hydroxylase Antikörper ist unkonjugiert

Applikation

  • 141
  • 104
  • 63
  • 55
  • 35
  • 27
  • 24
  • 22
  • 16
  • 14
  • 13
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • Bindungsspezifität

    • 20
    • 15
    • 14
    • 12
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer19

    Spezifität

    The antibody detects endogenous level of Tyrosine Hydroxylase only when phosphorylated at serine19.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    Immunogen

    Peptide sequence around phosphorylation site of pSer19 (A-V-S (p) -E-Q) derived from Rat pTyrosine Hydroxylase (TH) . Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    Isotyp

    IgG
  • Applikationshinweise

    Immunofluorescence: 1:100-1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target

    Tyrosine Hydroxylase (TH)

    Andere Bezeichnung

    Tyrosine Hydroxylase

    Hintergrund

    The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

    Molekulargewicht

    55-60 kDa

    NCBI Accession

    NP_036872

    UniProt

    P07101

    Pathways

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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