KRT8 Antikörper (pSer74)
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- Target Alle KRT8 Antikörper anzeigen
- KRT8 (Keratin 8 (KRT8))
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Bindungsspezifität
- pSer74
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KRT8 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF)
- Spezifität
- The antibody detects endogenous level of Keratin 8 only when phosphorylated at serine 74.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogen
- Peptide sequence around phosphorylation site of pSer74 (L-L-S (p) -P-L) derived from Human Keratin 8 (CK8) . Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Isotyp
- IgG
- Top Product
- Discover our top product KRT8 Primärantikörper
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- Applikationshinweise
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Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- KRT8 (Keratin 8 (KRT8))
- Andere Bezeichnung
- Keratin 8 (KRT8 Produkte)
- Synonyme
- CARD2 antikoerper, CK-8 antikoerper, CK8 antikoerper, CYK8 antikoerper, K2C8 antikoerper, K8 antikoerper, KO antikoerper, AA960620 antikoerper, AL022697 antikoerper, AU019895 antikoerper, Card2 antikoerper, EndoA antikoerper, Krt-2.8 antikoerper, Krt2-8 antikoerper, CYKER antikoerper, KRT2-8 antikoerper, KERATIN8 antikoerper, ck8 antikoerper, cyk8 antikoerper, k2c8 antikoerper, card2 antikoerper, krt2-5 antikoerper, MGC69490 antikoerper, KRT8 antikoerper, DreK8 antikoerper, cb186 antikoerper, krt2-8 antikoerper, sb:cb186 antikoerper, wu:fa20h05 antikoerper, wu:fa95h10 antikoerper, wu:fb96c06 antikoerper, zf-K8 antikoerper, zfk8 antikoerper, DKFZp468F2127 antikoerper, keratin 8 antikoerper, keratin 8 S homeolog antikoerper, KRT8 antikoerper, Krt8 antikoerper, krt8.S antikoerper, krt8 antikoerper
- Hintergrund
- Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
- Molekulargewicht
- 55 kDa
- NCBI Accession
- NP_002264
- UniProt
- P05787
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