MEK1 + MEK2 Antikörper (pSer217, pSer221)

Produktnummer ABIN362236

Der Kaninchen Polyklonal anti-MEK1 + MEK2 Antikörper (ABIN362236) detektiert spezifisch MEK1 + MEK2 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für MEK1 + MEK2 Antikörper (pSer217, pSer221) (ABIN362236)

Target: MEK1 + MEK2

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEK1 + MEK2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-MEK1 + MEK2 Antikörper

Bindungsspezifität: pSer217, pSer221

Spezifität: The antibody detects endogenous level of MEK1/MEK2 only when phosphorylated at serine 217/221.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: Peptide sequence around phosphorylation site of pSer217, 221 (I-D-S (p) -M-A) derived from Human MEK1, MEK2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu MEK1 + MEK2

Target: MEK1 + MEK2

Andere Bezeichnung: MEK1/MEK2

Hintergrund: Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

Molekulargewicht: 45 kDa

UniProt: Q02750