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BCR Antikörper (pTyr177)

BCR Reaktivität: Human, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN362226
  • Target Alle BCR Antikörper anzeigen
    BCR (Breakpoint Cluster Region (BCR))
    Bindungsspezifität
    • 31
    • 16
    • 14
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr177
    Reaktivität
    • 117
    • 76
    • 33
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 108
    • 13
    • 4
    Kaninchen
    Klonalität
    • 112
    • 13
    Polyklonal
    Konjugat
    • 58
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser BCR Antikörper ist unkonjugiert
    Applikation
    • 66
    • 39
    • 36
    • 30
    • 26
    • 26
    • 19
    • 15
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    The antibody detects endogenous level of Bcr only when phosphorylated at tyrosine 177.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around phosphorylation site of pTyr177 (P-F-Y (p) -V-N) derived from Human Bcr. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotyp
    IgG
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  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    BCR (Breakpoint Cluster Region (BCR))
    Andere Bezeichnung
    Bcr (BCR Produkte)
    Synonyme
    si:dkey-83d9.7 antikoerper, zK83D9.7 antikoerper, BCR antikoerper, ALL antikoerper, BCR1 antikoerper, CML antikoerper, D22S11 antikoerper, D22S662 antikoerper, PHL antikoerper, 5133400C09Rik antikoerper, AI561783 antikoerper, AI853148 antikoerper, mKIAA3017 antikoerper, breakpoint cluster region antikoerper, BCR, RhoGEF and GTPase activating protein antikoerper, bcr antikoerper, BCR antikoerper, Bcr antikoerper
    Hintergrund
    GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
    Molekulargewicht
    210 kDa
    NCBI Accession
    NP_004318
    UniProt
    P11274
    Pathways
    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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