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ICAM1 Antikörper (pTyr512)

Dieses Anti-ICAM1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ICAM1 in WB. Geeignet für Human.
Produktnummer ABIN362032

Kurzübersicht für ICAM1 Antikörper (pTyr512) (ABIN362032)

Target

Alle ICAM1 Antikörper anzeigen
ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reaktivität

  • 232
  • 53
  • 24
  • 23
  • 11
  • 7
  • 4
  • 3
  • 1
  • 1
Human

Wirt

  • 156
  • 111
  • 27
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 193
  • 108
  • 2
Polyklonal

Konjugat

  • 157
  • 25
  • 25
  • 19
  • 15
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ICAM1 Antikörper ist unkonjugiert

Applikation

  • 168
  • 142
  • 108
  • 70
  • 67
  • 50
  • 46
  • 31
  • 30
  • 26
  • 15
  • 14
  • 12
  • 10
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 23
    • 9
    • 9
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr512

    Spezifität

    The antibody detects endogenous level of ICAM-1 only when phosphorylated at tyrosine 512.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    Immunogen

    Peptide sequence around phosphorylation site of pTyr512 (K-K-Y (p) -R-L) derived from Human ICAM-1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    Isotyp

    IgG
  • Applikationshinweise

    Western blotting: 1:500-1:1000  

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target

    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

    Andere Bezeichnung

    ICAM-1

    Hintergrund

    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

    Molekulargewicht

    92 kDa

    NCBI Accession

    NP_000192

    UniProt

    P05362

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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