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Tyrosine Hydroxylase Antikörper (pSer31)

Name: Tyrosine Hydroxylase Antikörper (pSer31)
Brand: antibodies-online
SKU: ABIN361502
Price: 707.52 EUR
Availability: InStock

Der Kaninchen Polyklonal Anti-Tyrosine Hydroxylase Antikörper wurde für WB, IHC, ICC und ELISA validiert. Er ist geeignet, Tyrosine Hydroxylase in Proben von Ratte zu detektieren. Es sind 5+ Publikationen verfügbar.

Western blots of PC-12 cells incubated in the absence (Control) and presence of okadaic acid (OA, 1 µM for 60 min) showing specific immunolabeling of the ~60k TH phosphorylated at Ser31. (Tyrosine Hydroxylase Antikörper (pSer31))

Western blot of PC-12 cell lysate incubated in the absence (-) and presence (+) of okadaic acid (OA, 1 µM for 60 min) showing specific immunolabeling of the ~60 kDa tyrosine hydroxylase phosphorylated at Ser31. (Tyrosine Hydroxylase Antikörper (pSer31))

2 Abbildungen

(5 Referenzen)

Produktnummer ABIN361502

Kurzübersicht für Tyrosine Hydroxylase Antikörper (pSer31) (ABIN361502)

Target

Alle Tyrosine Hydroxylase (TH) Antikörper anzeigen

Tyrosine Hydroxylase (TH)

Reaktivität

Ratte

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser Tyrosine Hydroxylase Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA

Discover our top product TH Primärantikörper

Bindungsspezifität
20

15

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12

6

3

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1

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pSer31

Spezifität

Specific for endogenous levels of the ~60 kDa tyrosine hydroxylase protein phosphorylated at Ser31.

Kreuzreaktivität

Human, Maus, Ratte

Homologie

non-human primate

Produktmerkmale

Our Tyrosine Hydroxylase (Ser31) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Tyrosine Hydroxylase (Ser31) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.

Aufreinigung

Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser31 of rat tyrosine hydroxylase, conjugated to keyhole limpet hemocyanin (KLH).

Isotyp

IgG
anti-Tyrosine Hydroxylase (TH) antibody
TH Reaktivität: Human, Ratte, Maus, Hund, Huhn, Kaninchen, Drosophila melanogaster, Schwein, Zebrafisch (Danio rerio), Xenopus laevis, Meerschweinchen, Frettchen, Cat, Salmon, Salamander, Saccharomyces cerevisiae, Nagetiere, Wachtel, Polypterus senegalus, Taube, Phoronida, Parrot (Melopsittacus), Parrot, Opossum, Onchocerca, Molch, Zebra Finch, Mollusca, Sea Pansy, Sea Slug, Serinus canaria, Hai, Schaf, Spitzmaus, Snail, Schlange, Spatz, Squirrel Monkey, Starling, Forelle, Pute, Schildkröte, Water Buffalo, Emu, Alpaca, Amphibien, Aplysia californica, Avian, Bee, Blow Fly, Clams (Mytilus), Cockroach, Kabeljau, Koralle, Crab, Crayfish, Cynomolgus, Echidna, Macrobrachium rosenbergii (Giant fresh water prawn), Fisch, Fuchs, Frosch, Gecko, Wüstenrennmaus, Goldfisch, Guppy, Hamster, Iguana iguana, Lamprey, Blutegel, Eidechse, Hummer, Locust (Schistocerca) WB, IHC, IF, ICC, IEM Wirt: Maus Monoclonal LNC1 unconjugated

anti-Tyrosine Hydroxylase (TH) (AA 82-310) antibody
TH Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (AA 101-165) antibody
TH Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (pSer40) antibody
TH Reaktivität: Human, Ratte, Maus WB, IHC, IF, ICC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (pSer31) antibody
TH Reaktivität: Human, Ratte, Maus WB, IHC, IF, ICC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) antibody
TH Reaktivität: Human WB, IF, ICC, IHC (p), IHC (fro), IHC (wm) Wirt: Kaninchen Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (AA 486-514) antibody
TH Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (AA 34-301) antibody
TH Reaktivität: Ratte WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (pSer19) antibody
TH Reaktivität: Human, Ratte, Maus WB, IHC, IF, ICC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (AA 193-222), (Middle Region) antibody
TH Reaktivität: Ratte, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Dilution Range: ICC: 1:50-1:300
Dilution Range: WB Brain: 1:1000
Dilution Range: WB: 1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung

-20 °C

Informationen zur Lagerung

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Haltbarkeit

12 months
Calipari, Ferris, Melchior, Bermejo, Salahpour, Roberts, Jones: "Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations." in: Addiction biology, Vol. 19, Issue 2, pp. 145-55, (2014) (PubMed).

Izumi, Ezumi, Takada-Takatori, Akaike, Kume: "Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 139, Issue 2, pp. 466-78, (2014) (PubMed).

Nakashima, Mori, Kaneko, Hayashi, Nagatsu, Ota: "Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme." in: Biochemical and biophysical research communications, Vol. 407, Issue 2, pp. 343-7, (2011) (PubMed).

Jedynak, Ali, Haycock, Hope: "Acute administration of cocaine regulates the phosphorylation of serine-19, -31 and -40 in tyrosine hydroxylase." in: Journal of neurochemistry, Vol. 82, Issue 2, pp. 382-8, (2002) (PubMed).

Salvatore, Waymire, Haycock: "Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ." in: Journal of neurochemistry, Vol. 79, Issue 2, pp. 349-60, (2001) (PubMed).
Target

Tyrosine Hydroxylase (TH)

Andere Bezeichnung

Tyrosine Hydroxylase

Hintergrund

Synonyms: Dystonia 14 antibody, DYT14 antibody, DYT5b antibody, EC 1.14.16.2 antibody, OTTHUMP00000011225 antibody, OTTHUMP00000011226 antibody, ple antibody, Protein Pale antibody, TH antibody, The antibody, TY3H_HUMAN antibody, TYH antibody, Tyrosine 3 hydroxylase antibody, Tyrosine 3 monooxygenase antibody, Tyrosine 3-hydroxylase antibody, Tyrosine 3-monooxygenase antibody, Tyrosine hydroxylase antibody
Description Logic: Our Tyrosine Hydroxylase (Ser31) rabbit polyclonal phosphospecific primary antibody is produced . It detects Tyrosine Hydroxylase (Ser31) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.
Gene Name Alternatives: TH

Molekulargewicht

60 kDa

Gen-ID

25085

UniProt

P04177

Pathways

Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour