Dynamin 1 Antikörper (pSer774)
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- Target Alle Dynamin 1 (DNM1) Antikörper anzeigen
- Dynamin 1 (DNM1)
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Bindungsspezifität
- pSer774
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Reaktivität
- Ratte
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Wirt
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Schaf
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Klonalität
- Polyklonal
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Konjugat
- Dieser Dynamin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Spezifität
- Specific for the ~95k dynamin protein phosphorylated at Ser774. Labels the purified protein phosphorylated in vitro by cdk5 but not by PKC. Does not cross react with other purified substrates of cdk5 (e.g. amphiphysin and synapsin). Immunolabeling is blocked by (-phosphatase treatment.
- Kreuzreaktivität
- Ratte (Rattus)
- Homologie
- bovine, canine, chicken, human, mouse, non-human primates
- Aufreinigung
- Antigen Affinity Purified from Pooled Serum
- Immunogen
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser774 conjugated to KLH
- Top Product
- Discover our top product DNM1 Primärantikörper
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- Applikationshinweise
- Recommended Dilution: WB: 1:1000 IF (fixed cultured neurons): 1:1000 IHC (fixed cultured neurons): 1:1000 Quality Control: Western blots performed on each lot.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- Lagerung
- -20 °C
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- Target
- Dynamin 1 (DNM1)
- Andere Bezeichnung
- DNM1 (DNM1 Produkte)
- Synonyme
- DNM antikoerper, Dnm antikoerper, AI838169 antikoerper, Ftfl antikoerper, mKIAA4093 antikoerper, dnm antikoerper, DNM1 antikoerper, Dnm1 antikoerper, dnm1 antikoerper, si:dkey-246l19.2 antikoerper, dynamin 1 antikoerper, dynamin-1 antikoerper, dynamin 1a antikoerper, DNM1 antikoerper, Dnm1 antikoerper, BACOIKO008_37 antikoerper, PTRG_07818 antikoerper, PTRG_08097 antikoerper, dnm1 antikoerper, LOC100168088 antikoerper, LOC100199205 antikoerper, dnm1a antikoerper
- Hintergrund
- Dynamin is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis (Cousin et al., 2001, Graham et al., 2002, Tsuboi et al., 2002). Cyclin dependent protein kinase 5 phosphorylates dynamin at Ser774 and Ser778 that are the phosphorylation sites on dynamin phosphorylated in vivo (Tan et al., 2003). Phosphorylation of these sites on dynamin is thought to play a key role in synaptic vesicle trafficking.
- Molekulargewicht
- '95 kDa
- Gen-ID
- 140694
- UniProt
- P21575
- Pathways
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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