DDC Antikörper
Kurzübersicht für DDC Antikörper (ABIN361424)
Target
Alle DDC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Specific for the ~55k DDC protein.
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Kreuzreaktivität
- Ratte (Rattus)
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Homologie
- Bovine
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Aufreinigung
- Antigen Affinity Purified from Pooled Serum
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Immunogen
- SDS denatured, recombinant bovine aromatic DOPA decarboxylase expressed in E. coli and purified from inclusion bodies
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Applikationshinweise
- Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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Lagerung
- -20 °C
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- DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
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Andere Bezeichnung
- DDC
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Hintergrund
- DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC, DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002, Berry et al., 1996, Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). Anti-DOPA Decarboxylase Western blot of rat adrenal medulla. As shown in the autoradiograph, the antibody is specific for the ~55k DDC protein.
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Molekulargewicht
- '55 kDa
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Gen-ID
- 280762
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UniProt
- P27718
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Pathways
- Dopaminergic Neurogenesis
Target
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