SYN1 Antikörper

Produktnummer ABIN361409

Der Kaninchen Polyklonal Anti-SYN1-Antikörper wurde für WB, IHC, IF und IP validiert. Er ist geeignet, SYN1 in Proben von Rind (Kuh) zu detektieren.

Kurzübersicht für SYN1 Antikörper (ABIN361409)

Target: SYN1 (Synapsin I (SYN1))

Reaktivität: Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-SYN1 Antikörper

Spezifität: Specific for the ~78k synapsin I doublet in Western blots of rat brain extracts. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Antigen Affinity Purified from Pooled Serum

Immunogen: Native protein purified from bovine brain

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: WB: 1:1000 IHC, IF (frozen sections, unpublished observations): 1:2000 IP: 1 µg per 200 µg lysate Quality Control: Western blots performed on each lot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized

Lagerung: -20 °C

Details zu SYN1

Target: SYN1 (Synapsin I (SYN1))

Andere Bezeichnung: SYN1

Hintergrund: Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989, Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Anti-Synapsin I Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~78k synapsin I doublet protein.

Molekulargewicht: '78 kDa

Gen-ID: 281510

UniProt: P17599