RPH3A Antikörper (C-Term)
Kurzübersicht für RPH3A Antikörper (C-Term) (ABIN361408)
Target
Alle RPH3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- Specific for the ~82k rabphilin 3A protein.
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Kreuzreaktivität
- Ratte (Rattus)
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Homologie
- mouse, human, bovine, canine and non-human primate
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Aufreinigung
- Antigen Affinity Purified from Pooled Serum
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Immunogen
- Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
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Applikationshinweise
- Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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Lagerung
- -20 °C
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- RPH3A (Rabphilin 3A (RPH3A))
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Andere Bezeichnung
- RPH3A
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Hintergrund
- Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington?s disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001). Anti- Rabphilin 3A Western blot of rat cortex lysate showing specific immunolabeling of the ~82k rabphilin 3A.
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Molekulargewicht
- '82 kDa
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Gen-ID
- 171039
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UniProt
- P47709
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Pathways
- Synaptic Vesicle Exocytosis
Target
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