GRIN2B Antikörper (C-Term)

Produktnummer ABIN361395

Dieser Anti-GRIN2B Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von GRIN2B in WB, IHC, ELISA und IP. Geeignet für Ratte. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für GRIN2B Antikörper (C-Term) (ABIN361395)

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIN2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-GRIN2B Antikörper

Bindungsspezifität: C-Term

Spezifität: Specific for endogenous levels of the ~180 kDa NR2B subunit of the NMDA receptor. Immunolabeling is blocked by preadsorption of antibody with the fusion protein used to generate the antibody. No reactivity towards the NR2A and NR2C subunits.

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Our NMDA NR2B Subunit rabbit polyclonal primary antibody is produced in-house. It detects NMDA NR2B Subunit and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, IP.

Aufreinigung: Prepared from pooled rabbit serum by affinity purification using a column to which the fusion protein immunogen was coupled.

Immunogen: Fusion protein from the C-terminal region of the NR2B subunit of the rat NMDA receptor.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Dilution Range: IP: 3 μL per 200 μg lysate

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Reconstitute in 50 μl phosphate buffered saline (PBS: 137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use. After reconstitution it is recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Haltbarkeit: 12 months

Referenzen für anti-GRIN2B Antikörper (ABIN361395)

Brady, Diaz, Iuso, Everett, Valenzuela, Caldwell: "Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 3, pp. 1062-7, (2013) (PubMed).

Hicklin, Wu, Radcliffe, Freund, Goebel-Goody, Correa, Proctor, Lombroso, Browning: "Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 16, pp. 6650-5, (2011) (PubMed).

Kurup, Zhang, Xu, Venkitaramani, Haroutunian, Greengard, Nairn, Lombroso: "Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 17, pp. 5948-57, (2010) (PubMed).

Details zu GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Andere Bezeichnung: GRIN2B

Hintergrund:

Synonyms: AW490526 antibody, EIEE27 antibody, Glutamate [NMDA] receptor subunit epsilon 2 antibody, Glutamate [NMDA] receptor subunit epsilon-2 antibody, Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody, Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody, Glutamate receptor ionotropic NMDA2B antibody, Glutamate receptor subunit epsilon 2 antibody, Glutamate receptor ionotropic NMDA2B (epsilon 2) antibody, GRIN 2B antibody, GRIN2B antibody, hNR 3 antibody, hNR3 antibody, MGC142178 antibody, MGC142180 antibody, MRD6 antibody, N methyl D asparate receptor channel subunit epsilon 2 antibody, N methyl D aspartate receptor subtype 2B antibody, N methyl D aspartate receptor subunit 2B antibody, N methyl D aspartate receptor subunit 3 antibody, N-methyl D-aspartate receptor subtype 2B antibody, N-methyl-D-aspartate receptor subunit 3 antibody, NMDA NR2B antibody, NMDA R2B antibody, NMDAR2B antibody, NMDE2 antibody, NMDE2_HUMAN antibody, NME2 antibody, NR2B antibody, NR3 antibody

Description Logic: Our NMDA NR2B Subunit rabbit polyclonal primary antibody is produced . It detects NMDA NR2B Subunit and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, IP.

Gene Name Alternatives: GRIN2B

Molekulargewicht: 180 kDa

Gen-ID: 24410

UniProt: Q00960

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity