NEFM Antikörper (C-Term)
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- Target Alle NEFM Antikörper anzeigen
- NEFM (Neurofilament Triplet M Protein (NEFM))
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Bindungsspezifität
- C-Term
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Reaktivität
- Ratte
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Wirt
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Huhn
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Klonalität
- Polyklonal
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Konjugat
- Dieser NEFM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Spezifität
- Specific for the ~145k Neurofilament M protein.
- Kreuzreaktivität
- Huhn, Rind (Kuh), Human, Maus, Ratte (Rattus)
- Aufreinigung
- Total IgY fraction
- Immunogen
- Preparation containing the extreme C-terminus expressed in and purified from E. Coli
- Top Product
- Discover our top product NEFM Primärantikörper
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- Applikationshinweise
- Recommended Dilution: WB: 1:5,000 IF: 1:1000 Quality Control: Western blots performed on each lot.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- total IgY fraction in PBS + 10 mM Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." in: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).
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Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." in: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).
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- Target
- NEFM (Neurofilament Triplet M Protein (NEFM))
- Andere Bezeichnung
- NEFM (NEFM Produkte)
- Hintergrund
- Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Anti-Neurofilament M Western blot of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein.
- Molekulargewicht
- '145 kDa
- Gen-ID
- 24588
- UniProt
- P12839
- Pathways
- Brown Fat Cell Differentiation
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