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NEFM Antikörper (C-Term)

Der Huhn Polyklonal Anti-NEFM-Antikörper wurde für WB und IF validiert. Er ist geeignet, NEFM in Proben von Ratte zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN361355

Kurzübersicht für NEFM Antikörper (C-Term) (ABIN361355)

Target

Alle NEFM Antikörper anzeigen
NEFM (Neurofilament Triplet M Protein (NEFM))

Reaktivität

  • 66
  • 43
  • 35
  • 8
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Ratte

Wirt

  • 45
  • 24
  • 10
  • 1
Huhn

Klonalität

  • 46
  • 34
Polyklonal

Konjugat

  • 52
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NEFM Antikörper ist unkonjugiert

Applikation

  • 66
  • 27
  • 21
  • 18
  • 14
  • 14
  • 13
  • 13
  • 11
  • 10
  • 10
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 16
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    Specific for the ~145k Neurofilament M protein.

    Kreuzreaktivität

    Huhn, Rind (Kuh), Human, Maus, Ratte (Rattus)

    Aufreinigung

    Total IgY fraction

    Immunogen

    Preparation containing the extreme C-terminus expressed in and purified from E. Coli
  • Applikationshinweise

    Recommended Dilution: WB: 1:5,000 IF: 1:1000 Quality Control: Western blots performed on each lot.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    total IgY fraction in PBS + 10 mM Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C
  • Glass, Kelm-Nelson, Szot, Lake, Connor, Ciucci: "Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." in: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).

  • Target

    NEFM (Neurofilament Triplet M Protein (NEFM))

    Andere Bezeichnung

    NEFM

    Hintergrund

    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Anti-Neurofilament M Western blot of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein.

    Molekulargewicht

    '145 kDa

    Gen-ID

    24588

    UniProt

    P12839

    Pathways

    Brown Fat Cell Differentiation
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