Mitochondria Antikörper

Produktnummer ABIN361348

Produktdetails

Target: Mitochondria

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Spezifität: Specific for human mitochondria in all cell types. The antibody works on acetone fixed and 2% paraformaldehyde fixed cells. The antibody also works for immunohistochemistry on 2% paraformaldehyde fixed (5-10 minutes) cryostat sections.

Kreuzreaktivität: Human

Aufreinigung: Protein A purified

Immunogen: Human cell homogenate

Klon: 113-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: WB: 1:1,000 IHC: 1:800 IF: 1:800 Quality Control: Western blots performed on each lot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μL in PBS

Lagerung: -20 °C

Referenzen

Bussard, Smith: "Human breast cancer cells are redirected to mammary epithelial cells upon interaction with the regenerating mammary gland microenvironment in-vivo." in: PLoS ONE, Vol. 7, Issue 11, pp. e49221, (2012) (PubMed).

Antigendetails

Target: Mitochondria

Hintergrund: Mitochondria are most commonly known as the power plants of the cell as they produce ATP, but they are also involved in many other important cellular processes such as cell signaling, growth and differentiation (McBride et al., 2006). In addition, mitochondria have been shown to play a role in apoptosis (Green 1998). This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.

Molekulargewicht: '60 kDa