EGFL7
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
Western Blot (1-5 μg/mL) using the appropriate secondary reagents to detect HumanVE-Statin/EGFL-7. Immunohistochemistry on Frozen Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore in sterile water/PBS to a concentration of 0.1-1.0 mg/mL.
Buffer
PBS
Konservierungsmittel
Without preservative
Handhabung
This product is photosensitive and should be protected from light
Lagerung
4 °C
Informationen zur Lagerung
Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Target
EGFL7
(EGF-Like-Domain, Multiple 7 (EGFL7))
Andere Bezeichnung
EGFL7
Hintergrund
EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.Synonyms: EGF like protein 7, EGF-like protein 7, Epidermal growth factor-like protein 7, MEGF7, Multiple EGF-like domains protein 7, Multiple epidermal growth factor-like domains protein 7, NOTCH4-like protein, PRO1449, UNQ187, VE-statin, Vascular endothelial statin, Zneu1