IL17 Receptor B Antikörper (Extracellular Domain)

Produktnummer ABIN360915

Dieses Anti-IL17 Receptor B-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von IL17 Receptor B in WB. Geeignet für Maus.

Kurzübersicht für IL17 Receptor B Antikörper (Extracellular Domain) (ABIN360915)

Target: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL17 Receptor B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 9J28

Produktdetails anti-IL17 Receptor B Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: This antibody detects Mouse IL-17BR. No cross activity with Mouse IL-17R.

Aufreinigung: Protein A/G Affinity Chromatography

Immunogen: Recombinant protein of IL-17B R extracellular domain.

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS without stabilizer

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IL17 Receptor B

Target: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Andere Bezeichnung: IL17RB / IL17BR

Hintergrund: Recently, a number of cytokines belonging to the interleukin IL17 family have been identified. These are termed as IL17B, IL17C and IL17E. IL17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL17B, C, and E like IL17 are able to induce proinflammatory responses. However, they do not bind to the IL17 receptor suggesting that additional IL17R related receptor might exist. Receptor for IL17B and IL17E have been independently isolated and have been designated as EV127 (in mouse) and IL17RH1 (in human), respectively. IL17E induces activation of NFkB pathway and like IL17 also induces production of IL8. IL17RH1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.Synonyms: Cytokine receptor CRL4, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17RB, Interleukin-17 receptor B, Interleukin-17B receptor

Gen-ID: 50905

NCBI Accession: NP_062529

UniProt: Q9JIP3