IL17RA Antikörper (Extracellular Domain)
Kurzübersicht für IL17RA Antikörper (Extracellular Domain) (ABIN360914)
Target
Alle IL17RA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- Extracellular Domain
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Spezifität
- This antibody detects IL-17R. No cross activity to IL-17B R.
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Aufreinigung
- Protein A/G affinity chromatography
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Immunogen
- Recombinant protein of IL-17R extracellular domain.
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Isotyp
- IgG2
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Applikationshinweise
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL17RA (Interleukin 17 Receptor A (IL17RA))
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Andere Bezeichnung
- CD217 / IL17RA
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Hintergrund
- Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq]Synonyms: CDw217, IL-17 receptor, IL17R, Interleukin-17 receptor A
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Gen-ID
- 16172
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NCBI Accession
- NP_032385
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UniProt
- Q60943
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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