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IL17RA Antikörper (Extracellular Domain)

Der Ratte Monoklonal Anti-IL17RA-Antikörper wurde für WB validiert. Er ist geeignet, IL17RA in Proben von Maus zu detektieren.
Produktnummer ABIN360914

Kurzübersicht für IL17RA Antikörper (Extracellular Domain) (ABIN360914)

Target

Alle IL17RA Antikörper anzeigen
IL17RA (Interleukin 17 Receptor A (IL17RA))

Reaktivität

  • 67
  • 49
  • 14
Maus

Wirt

  • 77
  • 10
  • 3
  • 3
Ratte

Klonalität

  • 75
  • 18
Monoklonal

Konjugat

  • 45
  • 10
  • 8
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IL17RA Antikörper ist unkonjugiert

Applikation

  • 71
  • 36
  • 19
  • 15
  • 13
  • 13
  • 12
  • 11
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

10B27
  • Bindungsspezifität

    • 15
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain

    Spezifität

    This antibody detects IL-17R. No cross activity to IL-17B R.

    Aufreinigung

    Protein A/G affinity chromatography

    Immunogen

    Recombinant protein of IL-17R extracellular domain.

    Isotyp

    IgG2
  • Applikationshinweise

    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Rekonstitution

    Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    IL17RA (Interleukin 17 Receptor A (IL17RA))

    Andere Bezeichnung

    CD217 / IL17RA

    Hintergrund

    Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq]Synonyms: CDw217, IL-17 receptor, IL17R, Interleukin-17 receptor A

    Gen-ID

    16172

    NCBI Accession

    NP_032385

    UniProt

    Q60943

    Pathways

    SARS-CoV-2 Protein Interaktom
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