LGALS7 Antikörper

Produktnummer ABIN360888

Der Ratte Monoklonal anti-LGALS7 Antikörper (Klon 8J52) (ABIN360888) detektiert spezifisch LGALS7 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für LGALS7 Antikörper (ABIN360888)

Target: LGALS7 (Galectin 7 (LGALS7))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser LGALS7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 8J52

Produktdetails anti-LGALS7 Antikörper

Aufreinigung: Protein A/G Affinity Chromatography

Sterilität: 0.2 μm filtered

Immunogen: Purified Recombinant Mouse Galectin-7 Remarks: Mouse myeloma fused with spleen cells from a Rat

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: 0.2 μm filtered solution in PBS, None

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LGALS7

Target: LGALS7 (Galectin 7 (LGALS7))

Andere Bezeichnung: Galectin-7

Hintergrund: Galectins belong to a family of related beta-galactoside-binding lectins, also referred to as S-type or S-Lac lectins. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. Galectin 7 is thought to be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Galectin 7 has been implicated in apoptosis and is believed to upregulate MMP9 and as such be involved in the progression of tumorigenesis. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.Synonyms: Gal-7, HKL-14, LGALS7, LGALS7B, PI7, PIG1, p53-induced gene 1 protein

Gen-ID: 10090

UniProt: O54974