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DUSP10 Antikörper (N-Term)

DUSP10 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN360788
  • Target Alle DUSP10 Antikörper anzeigen
    DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 52
    • 29
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 48
    • 3
    • 1
    Kaninchen
    Klonalität
    • 50
    • 2
    Polyklonal
    Konjugat
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DUSP10 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 29
    • 18
    • 13
    • 13
    • 8
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to DUSP10.
    Aufreinigung
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DUSP10.
    Isotyp
    Ig Fraction
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    Discover our top product DUSP10 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
    Andere Bezeichnung
    DUSP10 / MKP5 (DUSP10 Produkte)
    Synonyme
    DUSP10 antikoerper, MKP-5 antikoerper, MKP5 antikoerper, 2610306G15Rik antikoerper, AI158871 antikoerper, Mkp-5 antikoerper, Mkp5 antikoerper, dual specificity phosphatase 10 antikoerper, DUSP10 antikoerper, Dusp10 antikoerper
    Hintergrund
    Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP10 binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique, it is evenly distributed in both the cytoplasm and the nucleus. The protein is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli.Synonyms: Dual specificity protein phosphatase 10, MAP kinase phosphatase 5, MKP-5, Mitogen-activated protein kinase phosphatase 5
    Gen-ID
    11221, 9606
    UniProt
    Q9Y6W6
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