BAIAP2 Antikörper (C-Term)

Produktnummer ABIN360705

Dieses Anti-BAIAP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BAIAP2 in WB, IHC (p) und EIA. Geeignet für Human und Maus.

Kurzübersicht für BAIAP2 Antikörper (C-Term) (ABIN360705)

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAIAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-BAIAP2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to BAIAP2.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BAIAP2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Andere Bezeichnung: BAIAP2

Hintergrund: BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.Synonyms: BAI-associated protein 2, BAI1-associated protein 2, BAP2, Brain-specific angiogenesis inhibitor 1-associated protein 2, FLAF3, Fas ligand-associated factor 3, IRS-58, IRSp53, IRSp53/58, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa

Gen-ID: 10458

NCBI Accession: NP_001138360

UniProt: Q9UQB8