Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (C-Term) Antikörper

Produktnummer ABIN360614

Der Kaninchen Polyklonal Anti--Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, in Proben von Human und Maus zu detektieren.

Kurzübersicht für Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (C-Term) Antikörper (ABIN360614)

Target: Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to UCK.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human UCK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Antigendetails

Target: Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)

Andere Bezeichnung: CMPK1

Hintergrund: UCK1 (Uridine-cytidine kinase 1) phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. This enzyme does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Of note, UCK1 is able to use either ATP or GTP as a phosphate donor. UCK1 also possesses the ability to phosphorylate a number of cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.Synonyms: CMK, CMPK, Cytidine monophosphate kinase, Cytidylate kinase, Deoxycytidylate kinase, UCK, UMK, UMP-CMP kinase, UMP/CMP kinase, UMP/CMPK, UMPK, Uridine monophosphate kinase, Uridine monophosphate/cytidine monophosphate kinase

Gen-ID: 51727, 9606

UniProt: P30085

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process