TLK2 Antikörper (Middle Region)
-
- Target Alle TLK2 Antikörper anzeigen
- TLK2 (Tousled-Like Kinase 2 (TLK2))
-
Bindungsspezifität
- Middle Region
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser TLK2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Aufreinigung
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human TLK2.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product TLK2 Primärantikörper
-
-
- Applikationshinweise
-
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
- Target
- TLK2 (Tousled-Like Kinase 2 (TLK2))
- Andere Bezeichnung
- TLK2 (TLK2 Produkte)
- Hintergrund
- TLK2, a member of the Ser/Thr protein kinase family, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase. It is inactivated by phosphorylation at Ser-750, potentially by CHK1. TLK2 heterodimerizes with TLK1. This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.Synonyms: PKU-alpha, Serine/threonine-protein kinase tousled-like 2, Tousled-like kinase 2
- Gen-ID
- 5874
- UniProt
- Q86UE8
-