PIM3 Antikörper (C-Term)

Produktnummer ABIN359340

Produktdetails anti-PIM3 Antikörper

Target: PIM3 (Pim-3 Oncogene (PIM3))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to PIM3.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PIM3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Protokoll: 1. Mikkers, H. , et al. , Mol. Cell. Biol. 24(13): 6104-6115 (2004). 2. Eichmann, A. , et al. , Oncogene 19(9): 1215-1224 (2000).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu PIM3

Target: PIM3 (Pim-3 Oncogene (PIM3))

Andere Bezeichnung: PIM3 (PIM3 Produkte)

Synonyme: pim1-a antikoerper, pim-3 antikoerper, BC026639 antikoerper, Kid1 antikoerper, Serine/threonine-protein kinase Pim-3 antikoerper, Pim-3 proto-oncogene, serine/threonine kinase S homeolog antikoerper, Pim-3 proto-oncogene, serine/threonine kinase antikoerper, pim-3 oncogene antikoerper, proviral integration site 3 antikoerper, pim3 antikoerper, pim3.S antikoerper, PIM3 antikoerper, Pim3 antikoerper

Hintergrund: PIM3 is a memberof the Ser/Thr protein kinase family that may be involved in cell cycle progression and anti-apoptosis process. This protein has been implicated in proliferation of human hepatoma cell lines. PIM3 is widely expressed, with the exception of no expression observed in colon, thymus, and small intestine. PIM3 is expressed in human hepatoma cell lines but not in normal liver tissues.Synonyms: PIM-3, Serine/threonine-protein kinase pim-3

Gen-ID: 415116, 9606

UniProt: Q86V86

Pathways: Negative Regulation of Hormone Secretion